Sheriff Henry Trochesset said the prisoner had ingested some sort of drugs at the Galveston County Courthouse and was taken to the hospital for treatment.
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At one point, the prisoner took off running at the hospital. A deputy caught up with the man, and fired his weapon inside Parking Garage No. 2.
The inmate was taken to the emergency center for a gunshot wound. The deputy who fired the weapon was not injured.
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The Texas Rangers are investigating the shooting.