The Houston Police Department said the crash happened in the 1900 block of Blalock Road at about 4:25 p.m.
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According to police, a 57-year-old woman was driving a red Toyota Corolla along Campbell Road and going through the intersection of Blalock Road with a green light.
That's when another driver in a silver Hyundai Santa Fe allegedly ran a red light on Blalock Road and hit the woman's vehicle.
HPD said the woman was pronounced dead at the scene. The woman's passenger and the 35-year-old driver of the Hyundai were reportedly taken to the hospital with non-life-threatening injuries.
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The driver accused of running the red light was questioned, but authorities said no charges had been filed.
The deadly crash remains under investigation.