The deadly collision occurred shortly before 4 p.m. Tuesday on the northbound lanes of Highway 146.
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The accident involved a black pickup that appeared to be nearly destroyed beneath the rear of an 18-wheeler.
Initially, all lanes of the roadway were blocked for the official investigation. Drivers were being advised to divert to Highway 225.
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By about 9 p.m., officials reopened all lanes and the scene was cleared.
The accident remains under investigation and the man's identity has not yet been released.
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