It happened behind a vacant building in the 8900 block of Cullen Boulevard near Reed Road around 7 p.m. on Thursday.
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Officers say a caller said a woman had been shot behind the building. They later found her behind a car.
Detectives are hoping to speak with the caller as part of their investigation.
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The woman was rushed to the hospital shortly after officers arrived. She was later pronounced dead.
Police are currently looking for surveillance video in the area and speaking with witnesses.
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