Harris County Precinct 4 Constables responded to a report about a pedestrian being hit in the 25500 block of the Tomball Tollway.
Upon arrival, constables learned that a vehicle lost a tire and the tire struck two construction workers.
The victims were transported to a nearby hospital, but their conditions are unknown.
Investigators cleared the scene shortly after the incident.
Eyewitness News is working to learn more information about this developing story.