The Grimes County Sheriff's Office said deputies responded to reports of a missing child near Knob Hill Road at about 3 p.m. on Sunday.
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After law enforcement and family members searched the area, the boy was reportedly found unresponsive several hundreds of yards away in a small drainage pond.
Deputies said life-saving measures were performed to resuscitate the 2-year-old, who was taken to St. Joseph's Hospital in Navasota for further emergency treatment.
The sheriff's office said the child succumbed to his injuries and was pronounced dead at the hospital.
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An investigation into the boy's death is underway, and autopsy results are pending.