Harris County Sheriff's Office says deputies tried to stop the driver in northwest Harris County around 11:30 p.m. Thursday.
Deputies say the driver was speeding, failed to stop at a red light and went into more than one lane.
The driver, who authorities identified as Kaylup Deruise, a man in his 30s, took off and deputies chased him for 5 minutes before he clipped an innocent driver's car after running another red light.
Deruise then lost control and slammed into a tree on Barker Cypress and Tuckerton.
Deputies reported seeing Deruise throw objects out the window during the chase. They recovered a small bag they believe contains drugs, possibly methamphetamine.
The innocent driver was not hurt in the crash.