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Houston TranStar verified multi-vehicle crashes at 12:51 p.m. and at 1:42 p.m. on the main lanes in both directions on I-10 East Eastbound at Beltway 8 east.
SkyEye video from the scene showed crews working to clear what appears to be a car carrier trailer from the freeway.
SkyEye video shows big rig blocking main lanes on I-10 after crash
It is unclear what caused the initial crash, and no injuries were reported.
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Although the car carrier has since been removed from the freeway, the main lanes remain closed.
Authorities have not disclosed how long commuters can expect delays.
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