Deputies from the Victor Valley Sheriff's Station responded to the area of Highway 395 and Bartlett Avenue at about 3:15 p.m. regarding the inflatable house blowing away from a home near the 18200 block of Delicious Avenue.
Officials said the child was inside and fell out after the bounce house rolled onto Highway 395 and hit a vehicle traveling southbound.
The boy was transported by ambulance to a local hospital for treatment of minor injuries.
The driver of the vehicle had no injuries and was "shook up" from the ordeal, sheriff's officials said.