Houston police said the crash happened just before noon in the 6000 block of Main at Sunset Boulevard.
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According to police, the bicyclist and the dump truck were about to turn right when the incident happened. An initial investigation appeared to show the bicyclist may have been at fault.
Police have not immediately identified the woman or the truck driver. The company of the dump truck has also not been identified.
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HPD urged people to avoid the area as investigators process the scene.