As expected, the face of the Astros ball club got booed during his first spring training at-bat. That plate appearance wound up with a strikeout, which drew cheers from fans in the stands.
Altuve followed that at-bat with a double in the third inning that scored Myles Straw.
But with his third plate appearance, the star second baseman got hit by a pitch in the fifth inning by Nick Ramirez. It did not appear to be intentional.
VIDEO: ABC13's David Nuño recaps what happened
Jose Altuve booed and hit by a pitch during his spring training debut
The Astros dominated, though, beating Detroit 11-1.
The Astros' exhibition matchup Monday against the Tigers marked the club's first road game of their preseason.
But, so far, no matter as a visiting club or in their own home-away-from-home in West Palm Beach, Florida, the team is hearing the instant criticism from fans and facing the tension of being targeted by opposing pitchers.
In fact, at least one Las Vegas sports book is taking bets on how many times Astros batters would be hit by pitches.
In two games against the Nationals, signs berating the Astros about their cheating were confiscated.
Just before the weekend series against Washington, which plays spring training games in the same complex as the Astros, outfield Josh Reddick told reporters he and other teammates were being threatened. One threat, Reddick said, targeted his newborn twin sons.
MORE ASTROS AT SPRING TRAINING:
Fans heckling Astros at spring opener get signs confiscated
Fans heckling Astros at spring opener get signs confiscated
Josh Reddick says he and other Astros are getting death threats
The Houston Astros are concerned for their safety after getting death threats