George Springer also homered to help Dallas Keuchel coast in Houston's second straight romp by the exact same score.
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The Astros will go for a sweep in the best-of-five matchup Sunday at Fenway Park.
A day after Altuve hit three home runs in the playoff opener, he got things going with a two-out single in the first inning off Drew Pomeranz. Correa, who went 0 for 4 on Thursday, made it 2-0 when he launched a towering shot onto the train tracks atop left field.
Keuchel pitched into the sixth, allowing one run and three hits while striking out seven.
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The Associated Press contributed to this report.
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