The video above is from ABC13's Live Streaming Channel.
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HFD tweeted that the fire seemingly broke out at a complex located at 1919 Runnels Street near Navigation.
Heavy smoke could be seen on Houston Transtar cameras.
There have been no reports of any injuries or casualties at this time.
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It is unclear what started the blaze.
Drivers are urged to avoid the area due to heavy emergency traffic.
This is a developing story and will be updated as more information comes in.