That's according to his attorney, who says El Chapo is chronically sleep deprived, and as a result, is growing ill.
El Chapo says through his lawyers that he will plead guilty to drug trafficking if he is transferred to the U.S.
How Guzman escaped a Mexican prison
But, the attorney says the drug lord would only agree to extradition if U.S. officials agree not to keep him in isolation, and to house him in a medium-security prison.
El Chapo has escaped twice from maximum security prisons in Mexico, including his most recent escape in July 2015.
He was re-arrested in January.
He is currently wanted in seven U.S. states. Mexican officials say they have already began working to extradite Guzman to the U.S.