This happened at the Walgreen's on Antoine and West Mount Houston in northwest Harris County.
Eyewitnesses say about six employees and customers were inside the store when two men rushed in waving guns and demanding money. Deputies said the thieves threatened the victims inside.
They say those crooks robbed the customers and cleaned out the cash registers before they ran off. No one was hurt but investigators say the victims were pretty shaken up as they interviewed them about the armed robbers.
Tametrice Harris lives nearby and says the robbery doesn't surprise her one bit.
"Well I mean they been breaking in houses, jacking people for their cars, snatching purses, so I been in the house before it gets dark," Harris said.
Other customers say they will use more caution when shopping in the area.
"I'm praying that someone will come forward with some information, if there are any witnesses," said Walgreen's shopper Tranesa Cephus.
Precinct One constable investigators will be reviewing surveillance video from the store in hopes of developing some leads on the gunmen involved in the robbery.
Constables also encourage anyone who might have information about the robbery to call Crimestoppers. That number is 713-222-TIPS.