Detectives say the shooting happened just after 1am.
Demetri Segura says the victim is his grandson, 21-year-old Jonathan Segura. He says his grandson was devoted to his wife and two kids, and was a hard worker. He can't imagine why anyone would want to hurt him.
According to police, Segura was driving westbound on Bissonnet in gold Buick LeSabre when he was intercepted by another car. Detectives say several cars surrounded his, and someone fired several shots into the LeSabre.
"As he was approaching the intersection of Bissonnet and Cook Road, several vehicles surrounded his vehicle and several shots were fired into the man's vehicle," said Sgt. Brian Harris with the Houston Police Department.
After the shots were fired, Segura's car accelerated, hit a utility pole and came to rest near a CITGO station.
Detectives say people inside a bar nearby heard the shots and the crash and ran to help. They pulled Segura out and tried to perform CPR. When paramedics arrived, they took over, but eventually pronounced him dead at the scene.
Police are looking for a red Dodge Magnum and a grey and black Cadillac that may have been involved in the shooting. Right now, they don't have a motive for the shooting, but they are looking into the meaning of the logo on the back of Segura's car.
"A Texans symbol on the back -- oftentimes in Houston when you see the Astros symbol or the Texans symbol, it doesn't necessarily mean that they're sports fans. It could indicate affiliations with other folks. But we don't know that," Sgt. Harris said.
Detectives are in the process of retracing Segura's steps in the hours leading up to the shooting. Authorities are asking anyone with information about what happened to give them a call.