This year is the 29th Annual BP MS 150, the largest event of its kind and the largest fundraising ride for the National Multiple Sclerosis Society.
"We have 13,000 participants," said Mark Negali with the National Multiple Sclerosis Society.
Each year it's a fun and lighthearted fundraiser. This year is the same, but the deadly bombing along the Boston marathon race will be on plenty of minds.
"We are saddened by the news that came out of the Boston marathon," Negali said.
The terrorist attack killed 3 people and injured nearly 200 more. It's enough to increase security measures for this race here at home.
"We are now evaluating if there will be additional security at the various sites," Negali said. "We are evaluating that with the guidance of the various local and state agencies. And we are definitely looking for them to have additional assets out there to identify any kind of threat."
But law enforcement officer and security expert Brian Hoffner says even with heightened awareness, there are never any guarantees with any public event so he says spectators and the average citizen have a responsibility too.
"It's impossible to secure a 75-mile bicycle route. It's just impossible so it's going to take more of everybody paying attention, watching for the out of the ordinary and not ignoring it," Hoffner said.
The National Multiple Sclerosis Society says incident commands in each county will be in constant communications with each other to ensure safety.