It happened around 4am on Collins at Gulfbank.
A 25-year old man suffered second-degree to his arms and three of his relatives were taken to Memorial Hermann Hospital in stable condition. A neighbor noticed the burning home and called 911.
"I woke up to the bathroom and I saw a light through my window and I looked through and see the house on fire," said neighbor Julio Chavez.
Firefighters say the fire destroyed the home as well as a car.
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