It happened at the intersection of Hollywood and Brown Wood Street.
According to officials with the Cloverleaf Volunteer Fire Department, four firefighters were their way to run a few errands. They were less than a block from the fire station when officials say the driver of a black Dodge pickup slammed into the side of the fire truck, flipping the emergency vehicle over.
According to witnesses, the pickup truck driver ran a stop sign.
"The truck and come hit the fire department truck, and dumped over" witness Rene Vences said.
"It's horrible. I just --- my brother. They said he's OK," said Elizabeth Beaver, whose brother was among the firefighters involved in the wreck.
Officials had to extricate two people out of the pickup. They were both taken to Ben Taub with serious injuries.
Four firefighters also were transported to be treated for minor injuries.
Take ABC13 with you!
Download our free apps for iPhone, iPad, Android and Blackberry devices