Abilene Police Chief Stan Standridge says the man died at a hospital following Wednesday morning's shooting. The wife wasn't hurt.
The woman called 911 to say her estranged spouse was in her bedroom. Police say the man apparently removed a window air conditioning unit to get inside and threatened to kill her. He then allegedly walked to the backyard.
Standridge says the 49-year-old man, whose name wasn't immediately released, had a loaded revolver. The suspect allegedly pointed the gun at officers and wouldn't surrender.
Both officers opened fire and shot him several times.
The officers have been put on administrative leave during a review of the incident.