According to investigators, two men were working on a car's engine on Lidston near Hansford around 11pm Saturday when they were approached by the two shooters.
It's not clear exactly what happened next, but the gunmen shot the two men.
One victim was shot in the abdomen and the other was shot in the shoulder. Both men were taken to Ben Taub General Hospital in serious but stable condition.
Police have not yet released a motive for the shooting and there is no description of the suspects at this time. Anyone with information can call Crime Stoppers.