Ronnette Daniels, 42, was last seen around 7pm Friday near her home on Avenue L in Galveston.
According to officials, she was last seen wearing pajamas -- a purple top with lavender bottoms -- and purple slippers.
No other details were released.
If you have any information, you are urged to call the Galveston Police Department at 409-765-3702 or Texas EquuSearch at 281-309-9500.