Police identified the victims Saturday -- a day after the tragic accident.
The crash happened around 2:30am Friday on North Sam Houston Tollway at North Sam Plaza.
According to investigators, 45-year-old Michael Winfield, was driving an 18-wheeler near the toll plaza just east of Antoine when the truck hit a concrete barrier. Police said the truck then hit an empty toll booth went airborne before it landed on a sports utility vehicle.
Winfield and the driver of the SUV -- 19-year-old Alexandria Collins-Flores -- were both killed.
Police believe Winfield was traveling at least 45 miles per hour and he likely fell asleep at the wheel.
Investigators said Flores had stopped to put cash in the toll plaza when the 18-wheeler landed on top of her SUV.
Winfield's family told us they want to send their sincere condolences to the family of Flores.
"The other family is going through what we're going through," relative Derrick Steptoe said. "We send our deepest condolences to the other family. We feel for Alexandria Flores, and they are in our prayers."
According to his family, Winfield was a professional truck driver. He was returning home after picking up a load in Dallas. He had been a truck driver for about 10 years and recently took a job as a local driver so he could be closer to his loved ones.
"It's been horrific. We've lost a great one," Steptoe said. "[He was] the main backbone of the family."
Funeral arrangements are pending at this time.