The accident on eastbound I-30 happened shortly before 2 a.m. Police say the truck driver and two people from the car were transported to hospitals with apparently non-life threatening injuries. Another person was seen being assisted at the scene.
Police are investigating why the truck apparently struck the median.
Crews worked to clear the debris. Texas Department of Transportation spokesman Mike Shannon says the damaged roadway will be examined before I-30 is allowed to reopen.