Tens of thousands of music fans crowded downtown Puerta de Alcala and Caja Magica to hear acts by Jared Leto and Shakira. Lady Gaga beamed her acceptance speech from Budapest, Hungary, where she is on tour.
Best New Act went to KE$HA, while the 16-year-old Justin Bieber won the Best Male Artist award, Paramore the Best Alternative act, and Eminem got the Best Hip Hop award.
The MTV Global Icon award went to Jon Bon Jovie, and Katy Perry got Best Video.