The Food and Drug Administration has convened the panel to help untangle reams of conflicting data over whether the former blockbuster Avandia increases heart risks.
The FDA is not required to follow the group's advice, though it often does.
Avandia has been under federal scrutiny since 2007, when an analysis first suggested it might cause heart attack.
The panel will vote later this afternoon on whether to withdraw GlaxoSmithKline's drug.