The commission on Tuesday released its list based on a "nutrition label" rating popular songs on healthy relationship themes.
Mario's "Break Up" topped the list of the most unhealthy relationship songs of 2009.
Among the panel's top 10 songs with healthy themes: "Miss Independent" by Ne-Yo and "Meet Me Halfway" by the Black Eyed Peas.
The commission says its program aims to teach teens how to evaluate popular media, and help parents talk to teens about healthy relationships.