Byrd scored 12 points and matched that number with a dozen rebounds. Marcelle Goins added 10 points for the Golden Lions.
UAPB (12-13, 8-6 Southwestern Athletic Conference) led 40-27 at the half.
Prairie View (7-18, 5-8) couldn't overcome a bad night from long distance. The Panthers made none of the six 3-pointers they attempted.
Blake Thompson led Prairie View with 14 points, while Derek Johnson scored 10.
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